Lucas Miranda

¡Hola! Soy investigador postdoctoral en EPFL MLBio, dirigido por Maria Brbić. Antes también fui postdoc en el Instituto Max Planck de Bioquímica (MLSB, Karsten Borgwardt). Obtuve mi doctorado en 2024 de la Universidad Técnica de Munich (TUM), bajo la supervisión de Bertram Müller-Myhsok. Mi investigación se centra en el desarrollo de métodos de aprendizaje automático para problemas de bioinformática y medicina, con un enfoque particular en ómicas espaciales.
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Novedades

Nuevo postdoc en EPFL

Empecé un nuevo trabajo como investigador postdoctoral en EPFL, como parte de MLBIO.

Ăšltimas publicaciones

Nuclear proteome reveals microtubule-associated protein regulating fate and disease

F Merino, L Miranda, A Kumar, Y Li, DK Sundaramoorthy, J Merl-Pham, EM Schentarra, C Steinek, V Pravata, C Kittock, M Bürkle, BA Hersbach, F Giesert, R Jungmann, LJ Pilaz, SM Hauck, S Cappello, M Götz
Cell, 2026
ArtĂ­culo  

Early detection of ampicillin susceptibility in Enterococcus faecium with MALDI-TOF/MS and machine learning

T Pichl, L Miranda, MT Warkotsch, N Wantia, K Borgwardt, J Sattler
Journal of Global Antimicrobial Resistance, 2026
ArtĂ­culo   Blog  

Single-cell spatial proteomics maps human liver zonation patterns and their vulnerability to disruption in tissue architecture

C Weiss, LA Brown, L Miranda, P Pellizzoni, S Steigerwald, K Remmert, J Hernandez, K Borgwardt, DE Kleiner, S Ben-Moshe, FA Rosenberger, N Porat-Shliom, M Mann
Nature Metabolism, 2026
ArtĂ­culo  

Conformal Prediction with Knowledge Graphs for Reliable Antimicrobial Resistance Detection with MALDI-TOF Mass Spectra

N Corvelo Benz‡, L Miranda‡, D Chen, J Sattler, K Borgwardt
Journal of Computational Biology, 2026
ArtĂ­culo   CĂłdigo   Blog  

Loss of noradrenergic Fkbp5 disrupts social behavior and norepinephrine dynamics in the basolateral amygdala

J Bordes, L Stont, T Bajaj, S Chang, T Ebert, L Miranda, P Schlegel, M Reinhardt, M Pöhlmann, Y Mecdad, L van Doeselaar, H Yang, V Kovarova, S Mitra, M De Angelis, B Müller-Myhsok, JM Deussing, A Beyeler, NC Gassen, MV Schmidt
bioRxiv, 2025
arXiv arXiv  

Epigenomic embedding of childhood adversity links to disease risk and chronic immune changes

D Czamara, D Juntilla, A Nounu, AL Weihs, M Erhart, L Maier, M Leskien, J Tuhkanen, AD Scherff, N Yusupov, J Hagenberg, AS Fröhlich, VN Karlbauer, S van der Auwera, T Brückl, J Kopf-Beck, S Egli, H Völzke, U Völker, A Weihs, A Teumer, J Winkelmann, H Prokisch, J Knauer-Arloth, L Feldmann, L Miranda, B Müller-Myhsok, BW Dunlop, WE Craighead, JC Felger, AH Miller, CB Nemeroff, F Hoffmann, S Entringer, C Buss, SM Winter, N Matosin, HS Mayberg, CM Heim, M Standl, J Lahti, K Räikkönen, E Greimel, G Schulte-Körne, HJ Grabe, A Peters, M Waldenberger, EB Binder
preprint, 2025
ArtĂ­culo  

Classification of social behavioral responses in stress and non-stress adult male mice with high precision

JM Restrepo-Lozano, M Teixeira, G Hernandez, L Miranda, A Mahmud, MV Schmidt, C Flores
NPP—Digital Psychiatry and Neuroscience, 2025
ArtĂ­culo  

Highlighting Genetic Differences between Barlow's Disease and Fibroelastic Deficiency via Genome-Wide Association Study Meta-Analyses

N Feirer, M Weber, K Knoll, L Miranda, M Yu, L Li, H Lahm, M Kameric, S Doppler, I Gottmann, P Lichtner, K Berger, M Lek, R Lange, H Schunkert, A Hagège, N Bouatia-Naji, B Müller-Myhsok, T Trenkwalder, P Gruber, M Krane, M Dreßen
The Thoracic and Cardiovascular Surgeon, 2025
ArtĂ­culo  

Sex-specific fear acquisition following early life stress is linked to amygdala and hippocampal purine and glutamate metabolism

J Bordes, T Bajaj, L Miranda, L van Doeselaar, L Brix, S Narayan, S Mitra, V Kovarova, MV Schmidt, M Springer, K Kleigrewe, B MĂĽller-Myhsok, N Gassen, MV Schmidt
Communications biology, 2024
ArtĂ­culo  

Deep clustering of animal motion tracking data: software development and applications to psychiatric preclinical research

L Miranda
Doctoral thesis, Technical University of Munich (TUM), 2024
Página   CĂłdigo  

Genome-Wide Association Study in 2,140 Patients and Subtype Meta-analyses of Barlow's Disease and Fibroelastic Deficiency Identify Novel Risk Loci for Mitral Valve Prolapse

N Feirer, M Weber, K Knoll, L Miranda, M Yu, H Lahm, M Kameric, S Doppler, I Neb, P Lichtner, M Lek, R Lange, H Schunkert, A Hagège, N Bouatia-Naji, B Müller-Myhsok, T Trenkwalder, P Gruber, M Krane, M Dreßen
The Thoracic and Cardiovascular Surgeon, 2024
ArtĂ­culo  

Early life adversity shapes social subordination and cell type–specific transcriptomic patterning in the ventral hippocampus

A Kos‡, JP Lopez‡, J Bordes, C de Donno, J Dine, E Brivio, S Karamilhalev, S Gasperoni, A Dick, L Miranda, M Büttner, R Stoffel, C Flachskamm, F Theis, MV Schmidt, A Chen
Science Advances, 2023
ArtĂ­culo  

Multimodal learning in clinical proteomics: enhancing antimicrobial resistance prediction models with chemical information

G Visonà‡, D Duroux‡, L Miranda, E Sukei, Y Li, K Borgwardt, C Oliver
Bioinformatics, 2023
ArtĂ­culo   CĂłdigo   Blog  

Advancing social behavioral neuroscience by integrating ethology and comparative psychology methods through machine learning

J Bordes, L Miranda, B MĂĽller-Myhsok, MV Schmidt
Neuroscience & Biobehavioral Reviews, 2023
ArtĂ­culo  

Automatically annotated motion tracking identifies a distinct social behavioral profile following chronic social defeat stress

J Bordes‡, L Miranda‡, M Reinhardt, S Narayan, J Hartmann, E Newman, LM Brix, L van Doeselaar, C Engelhardt, L Dillmann, S Mitra, K Ressler, B Pütz, F Agakov, B Müller-Myhsok, MV Schmidt
Nature Communications, 2023
Sitio web   Página   ArtĂ­culo   CĂłdigo  

DeepOF: A Python package for supervised and unsupervised pattern recognition in mice motion tracking data

L Miranda, J Bordes, B PĂĽtz, MV Schmidt, B MĂĽller-Myhsok
Journal of Open Source Software, 2023
Sitio web   ArtĂ­culo   CĂłdigo  

miRNAs associated with endoplasmic reticulum stress and unfolded protein response during decidualization

E Soczewski, JM Murrieta-Coxca, L Miranda, P Fuentes-Zacarías, R Gutiérrez-Samudio, E Grasso, M Martí, C Pérez Leirós, D Morales-Prieto, R Ramhorst
Reproductive BioMedicine Online, 2023
ArtĂ­culo  

Increasing resolution in stress neurobiology: from single cells to complex group behaviors

L Miranda‡, J Bordes‡, S Gasperoni, JP Lopez
Stress, 2023
ArtĂ­culo  

Systematic review of functional MRI applications for psychiatric disease subtyping

L Miranda, R Paul, B PĂĽtz, N Koutsouleris, B MĂĽller-Myhsok
Frontiers in Psychiatry, 2021
ArtĂ­culo  

Comprehensive identification of pathogenic gene variants in patients with neuroendocrine disorders

SA Vishnopolska, MF Mercogliano, MA Camilletti, AH Mortensen, D Braslavsky, A Kaselman, I Bergadá, F Olivieri, L Miranda, R Marino, P Ramírez, N Pérez Garrido, H Patiño Mejia, M Ciaccio, MI Di Palma, A Belgorosky, MA Martí, JO Kitzman, SA Camper, MI Perez-Millán
The Journal of Clinical Endocrinology & Metabolism, 2021
ArtĂ­culo  

The transcription factor NF-kB mediates thyrotropin-stimulated expression of thyroid differentiation markers

RC Geyesis, V peyret, M MartĂ­n, M Nazar, C Reale, CE Bernal Barquero, L Miranda, MA MartĂ­, P Vito, AM Masini-Repiso, JP Nicola
Thyroid, 2021
ArtĂ­culo