Lucas Miranda

Soy investigador postdoctoral en EPFL MLBio, dirigido por Maria Brbić. Anteriormente, también fui postdoc en el Instituto Max Planck de Bioquímica (MLSB, Karsten Borgwardt). Obtuve mi doctorado en 2024 de la Universidad Técnica de Munich (TUM), bajo la supervisión de Bertram Müller-Myhsok. Mi investigación se centra en el desarrollo de métodos de aprendizaje automático para problemas de bioinformática y medicina.

Publicaciones

Single-cell spatial proteomics maps human liver zonation patterns and their vulnerability to disruption in tissue architecture

C Weiss, LA Brown, L Miranda, P Pellizzoni, S Steigerwald, K Remmert, J Hernandez, K Borgwardt, DE Kleiner, S Ben-Moshe, FA Rosenberger, N Porat-Shliom, M Mann
Nature Metabolism, 2026

Artículo

Conformal Prediction with Knowledge Graphs for Reliable Antimicrobial Resistance Detection with MALDI-TOF Mass Spectra

N Corvelo Benz‡, L Miranda‡, D Chen, J Sattler, K Borgwardt
Journal of Computational Biology, 2026

Artículo Código

Loss of noradrenergic Fkbp5 disrupts social behavior and norepinephrine dynamics in the basolateral amygdala

J Bordes, L Stont, T Bajaj, S Chang, T Ebert, L Miranda, P Schlegel, M Reinhardt, M Pöhlmann, Y Mecdad, L van Doeselaar, H Yang, V Kovarova, S Mitra, M De Angelis, B Müller-Myhsok, JM Deussing, A Beyeler, NC Gassen, MV Schmidt
bioRxiv, 2025

arXiv

Classification of social behavioral responses in stress and non-stress adult male mice with high precision

JM Restrepo-Lozano, M Teixeira, G Hernandez, L Miranda, A Mahmud, MV Schmidt, C Flores
NPP—Digital Psychiatry and Neuroscience, 2025

Artículo

Early detection of ampicillin susceptibility in Enterococcus faecium with MALDI-TOF MS and machine learning

T Pichl, L Miranda, N Wantia, K Borgwardt, J Sattler
bioRxiv, 2025

arXiv

Detecting antimicrobial resistance through MALDI-TOF mass spectrometry with statistical guarantees using conformal prediction

N Corvelo Benz‡, L Miranda‡, D Chen, J Sattler, K Borgwardt
RECOMB, 2025

Página Artículo Código

Sex-specific fear acquisition following early life stress is linked to amygdala and hippocampal purine and glutamate metabolism

J Bordes, T Bajaj, L Miranda, L van Doeselaar, L Brix, S Narayan, S Mitra, V Kovarova, MV Schmidt, M Springer, K Kleigrewe, B Müller-Myhsok, N Gassen, MV Schmidt
Communications biology, 2024

Artículo

Deep clustering of animal motion tracking data: software development and applications to psychiatric preclinical research

L Miranda
Doctoral thesis, Technical University of Munich (TUM), 2024

Página Código

Early life adversity shapes social subordination and cell type–specific transcriptomic patterning in the ventral hippocampus

A Kos‡, JP Lopez‡, J Bordes, C de Donno, J Dine, E Brivio, S Karamilhalev, S Gasperoni, A Dick, L Miranda, M Büttner, R Stoffel, C Flachskamm, F Theis, MV Schmidt, A Chen
Science Advances, 2023

Artículo

Multimodal learning in clinical proteomics: enhancing antimicrobial resistance prediction models with chemical information

G Visonà‡, D Duroux‡, L Miranda, E Sukei, Y Li, K Borgwardt, C Oliver
Bioinformatics, 2023

Artículo Código

Advancing social behavioral neuroscience by integrating ethology and comparative psychology methods through machine learning

J Bordes, L Miranda, B Müller-Myhsok, MV Schmidt
Neuroscience & Biobehavioral Reviews, 2023

Artículo

Automatically annotated motion tracking identifies a distinct social behavioral profile following chronic social defeat stress

J Bordes‡, L Miranda‡, M Reinhardt, S Narayan, J Hartmann, E Newman, LM Brix, L van Doeselaar, C Engelhardt, L Dillmann, S Mitra, K Ressler, B Pütz, F Agakov, B Müller-Myhsok, MV Schmidt
Nature Communications, 2023

Página Artículo Código

DeepOF: A Python package for supervised and unsupervised pattern recognition in mice motion tracking data

L Miranda, J Bordes, B Pütz, MV Schmidt, B Müller-Myhsok
Journal of Open Source Software, 2023

Página Artículo Código

miRNAs associated with endoplasmic reticulum stress and unfolded protein response during decidualization

E Soczewski, JM Murrieta-Coxca, L Miranda, P Fuentes-Zacarías, R Gutiérrez-Samudio, E Grasso, M Martí, C Pérez Leirós, D Morales-Prieto, R Ramhorst
Reproductive BioMedicine Online, 2023

Artículo

Increasing resolution in stress neurobiology: from single cells to complex group behaviors

L Miranda‡, J Bordes‡, S Gasperoni, JP Lopez
Stress, 2023

Artículo

Systematic review of functional MRI applications for psychiatric disease subtyping

L Miranda, R Paul, B Pütz, N Koutsouleris, B Müller-Myhsok
Frontiers in Psychiatry, 2021

Artículo

Comprehensive identification of pathogenic gene variants in patients with neuroendocrine disorders

SA Vishnopolska, MF Mercogliano, MA Camilletti, AH Mortensen, D Braslavsky, A Kaselman, I Bergadá, F Olivieri, L Miranda, R Marino, P Ramírez, N Pérez Garrido, H Patiño Mejia, M Ciaccio, MI Di Palma, A Belgorosky, MA Martí, JO Kitzman, SA Camper, MI Perez-Millán
The Journal of Clinical Endocrinology & Metabolism, 2021

Artículo

The transcription factor NF-kB mediates thyrotropin-stimulated expression of thyroid differentiation markers

RC Geyesis, V peyret, M Martín, M Nazar, C Reale, CE Bernal Barquero, L Miranda, MA Martí, P Vito, AM Masini-Repiso, JP Nicola
Thyroid, 2021

Artículo